CCL26

CCL26

chemokine (C-C motif) ligand 26
Identifiers
Symbol CCL26
Alt. symbols SCYA26, MIP-4alpha, eotaxin-3, IMAC, MIP-4a, TSC-1
Entrez HUGO OMIM PDB 1G2T (RefSeq UniProt Locus q11.2

Chemokine (C-C motif) ligand 26 (CCL26) is a small cytokine belonging to the CC chemokine family that is also called Eotaxin-3, Macrophage inflammatory protein 4-alpha (MIP-4-alpha), Thymic stroma chemokine-1 (TSC-1), and IMAC. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4.[1][2] CCL26 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3.[3] This gene for chemokine is located on human chromosome 7.[4]

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