GBA2

GBA2

Glucosidase, beta (bile acid) 2
Identifiers
3.2.1.45
Orthologs
SpeciesHumanMouse

Non-lysosomal glucosylceramidase is an 3.2.1.45) activity.

Function

This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.[2]

See also

  • Closely related enzymes
    • 3.2.1.45
    • GBA3: acid β-glucosidase (cytosolic), 3.2.1.21

References

Further reading