Computerized tomography of hepatomegaly
Classification and external resources
ICD-10 R16..0
ICD-9-CM 789.1
MedlinePlus 003275

Hepatomegaly is the condition of having an enlarged liver. It is a non-specific medical sign having many causes, which can broadly be broken down into infection, direct toxicity, hepatic tumours, or metabolic disorder. Often, hepatomegaly will present as an abdominal mass. Depending on the cause, it may sometimes present along with jaundice.


  • Causes 1
    • Infective 1.1
    • Neoplastic 1.2
    • Cirrhotic 1.3
    • Metabolic 1.4
    • Drugs and toxins 1.5
    • Congenital 1.6
    • Others 1.7
  • Diagnosis 2
  • See also 3
  • External links 4






Drugs and toxins


  • Hemolytic anemia
  • Riedel's lobe is an extended, tongue-like, right lobe of the liver. It is not pathological; it is a normal anatomical variant and may extend into the pelvis. It is often mistaken for a distended gall bladder or liver tumour.
  • Polycystic disease
  • Cori's disease



A suspicion of hepatomegaly indicates a thorough medical history and physical examination, wherein the latter typically includes an increased liver span. Blood tests should be done, importantly liver-function series, which will give a good impression of the patient's broad metabolic picture.

An ultrasound of the liver can reliably detect a dilated biliary-duct system, which helps distinguish parenchymal liver disease from extrahepatic bile-duct obstruction. Ultrasound can also detect the characteristic texture of a cirrhotic liver, and can guide fine-needle aspiration of cysts, abscesses and tumours.

Computed tomography or (computerized tomography) (CT) can help to obtain more accurate anatomical information, and is unaffected by obesity or the presence of bowel gases.

See also

External links

  • National Institute of Health's Medline Plus Medical Encyclopedia: Hepatomegaly
  • Merck Manual: Hepatomegaly